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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1087 | Substance P | Neurokinin P | Endogenous Metabolite , Neurokinin receptor |
Substance P (Neurokinin P) (SP) is an undecapeptide (a peptide composed of a chain of 11 amino acid residues) member of the tachykinin neuropeptide family. | |||
TP1008 | Neurokinin A | α-Neurokinin,Substance K,Neuromedin L | Neurokinin receptor |
Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene. | |||
T7633 | Senktide | Neurokinin receptor | |
Senktide is an agonist of tachykinin NK3 receptor. | |||
T23316 | SB 218795 | Neurokinin receptor | |
SB 218795 is an effective and selective antagonist of NK3 with a Ki 13 nM for hNK3 which is about 90-fold and 7000-fold selectivity over hNK2 and hNK1. | |||
T16849 | SB-222200 | Neurokinin receptor | |
SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM). | |||
TP1086 | Men 10376 TFA(135306-85-3,free) | Men 10376 TFA,Neurokinin-2 receptor antagonist TFA | Neurokinin receptor |
Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 M for the nk-2 receptor in the small intestine of rats. | |||
T7209 | Maropitant | Neurokinin receptor | |
Maropitant is a selective neurokinin (NK1) receptor antagonist. | |||
TP1572 | GR-73632 | Neurokinin receptor | |
Potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens). | |||
T38144 | Elinzanetant | Neurokinin receptor | |
Elinzanetant is a dual antagonist of neurokinin (NK) receptors 1 and 3 and modulates reproductive hormone secretion. | |||
T15278 | Fezolinetant | ESN-364 | Neurokinin receptor |
Fezolinetant (ESN-364) is an antagonist of the neurokinin 3 receptor (NK3R). It is used for the treatment of menopausal hot flushes. | |||
T7549 | Talnetant | SB 223412 | Neurokinin receptor |
Talnetant (SB 223412) is a selective, competitive, brain-penetrant NK3 receptor antagonist with the ability to modulate mesolimbic and mesocortical dopaminergic neurotransmission | |||
T76429 | Neurokinin Receptor (393-407), rat | ||
Neurokinin Receptor (393-407), rat (SPR393–407), a fragment of the rat neurokinin 1 receptor (NK1R), undergoes rapid endocytosis and subsequent recycling to the plasma membrane upon substance P (SP) binding. This compoun... | |||
T8235 | L-732138 | Neurokinin receptor | |
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM) | |||
TP1883 | [Lys5,MeLeu9,Nle10]-NKA(4-10) | Neurokinin receptor | |
Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively). | |||
T17156 | Tradipitant | VLY-686,LY686017 | Neurokinin receptor |
Tradipitant (VLY-686) is an antagonist of neurokinin-1. | |||
T7554 | Substance P (7-11) | Substance P 7-11(TFA) | Others , Neurokinin receptor |
Substance P (7-11) (Substance P 7-11(TFA)) is a C-terminal fragment of Substance P . | |||
T16038 | Men 10376 | Neurokinin-2 receptor antagonist | CDK |
Men 10376 is a selective antagonist of tachykinin NK-2 receptor. It has a Ki of 4.4 μM for rat small intestine NK-2 receptor. | |||
T6905 | Netupitant | Ro 67-31898/000,CID 6451149 | Neurokinin receptor |
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM). | |||
T3716 | Rolapitant | SCH619734 | Neurokinin receptor |
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ... | |||
T7559 | Neurokinin A(4-10) | Neurokinin A(4-10)(TFA) | Neurokinin receptor |
Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor . |